I’d double check from one of the Hologram employees who reply on this forum but based on:
I dont think the Hologram SDK will work with your setup. Per Reuben “The SDK is entirely written to only detect modems that are mounted on the USB port” so I dont think it searches for Compatible modems on any COM ports. Note that even though most devices interface with the computer on a USB cable they are seen as virtual COM ports. I think Reuben means something different here.
Secondly, double check you have the latest SDK, it looks like support for the R410M may have come with v0.8.0 on changelog dated 7/19 per: hologram-python/CHANGELOG.md at c1af4988be88e963096634dc10ad5c3e19053559 · hologram-io/hologram-python · GitHub
Best of luck!, and definitely wait to hear from Hologram for a definitive answer.